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Primary signet ring cell carcinoma of the colon and rectum

longfeilujun 添加于 2018-7-12 22:31 | 978 次阅读 | 0 个评论

作者
Arifi S, Elmesbahi O, Amarti Riffi A
摘要
Colorectal primary signet ring cell carcinoma (SRCC) is a rare entity accounting for nearly 1% of all colorectal carcinomas. It is an independent prognostic factor associated with less favorable outcome. This aggressiveness is mainly due to the intrinsic biology of these tumors. Here is an overview of the literature related to clinicopathological features, molecular biology, and management of SRCC of the colon and the rectum.
详细资料
- 关键词: *Carcinoma, Signet Ring Cell/epidemiology/genetics/pathology/therapy; *Colonic Neoplasms/epidemiology/genetics/pathology/therapy; Genes, ras; Humans; Incidence; Loss of Heterozygosity; Microsatellite Instability; Mucin 5AC/metabolism; Mucin-2/metabolism; Mutation; Neoplasm Proteins/metabolism; Prognosis; *Rare Diseases/epidemiology/genetics/pathology/therapy; *Rectal Neoplasms/epidemiology/genetics/pathology/therapy; raf Kinases/genetics; Colorectal cancer; Molecular biology; Pathology; Signet r ...
- 文献种类: Journal Article
- 期刊名称: Bulletin du Cancer
- 期刊缩写: Bull Cancer
- 期卷页: 2015年第102卷第10期 880-888页
- 地址: Hassan II university hospital, Mohamed ben Abdullah University, School of medicine, Laboratory of cancer biology, Fez, Morocco; Hassan II university Hospital, Mohamed ben Abdullah University, School of medicine, Pathology department, Fez, Morocco; Laboratory of pathology Al Azhar, Fez, Morocco
- ISBN: 0007-4551
学科领域生物医药 » 临床医学
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