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有读书笔记有附件Correcting aberrant kinetochore microtubule attachments: an Aurora B-centric view

1 阿平 添加于 2009-5-22 01:35 | 3688 次阅读 | 2 个评论
  •  作 者

    Kelly AE, Funabiki H
  •  摘 要

    The directed movement of chromosomes during mitosis and meiosis relies on microtubule-mediated connections between spindle poles and kinetochores assembled on chromosomes. The molecular basis for the dynamic interaction between microtubules and kinetochores is just beginning to be unveiled. Here, focusing on the mitotic centromere kinase Aurora B, we review our current understanding of the signaling pathways that correct erroneous microtubule attachment at kinetochores. We evaluate several potential models that may explain how maloriented attachments are recognized and processed by the Aurora B pathway.
  •  详细资料

    • 关键词: Animals; Centromere/*metabolism; Kinetochores/*metabolism; Microtubules/*metabolism; Models, Biological; Protein-Serine-Threonine Kinases/*metabolism
    • 文献种类: Journal Article
    • 期刊名称: Current Opinion in Cell Biology
    • 期刊缩写: Curr Opin Cell Biol
    • 期卷页: 2009  21 1 51-58
    • 地址: The Rockefeller University, Laboratory of Chromosome and Cell Biology, 1230 York Avenue, New York, NY 10065, USA
    • ISBN: 1879-0410
    • 备注:PMID:19185479
  • 学科领域 生物医药 » 生物学

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  •  附 件

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  •  阿平 的文献笔记  订阅

    比较关心Aurora B

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!reply! shanghaiguisi 2013-1-21 16:43
实验室仪器零售 批发  性价比高  www.yusus.net  欢迎垂询
!reply! shanghaiguisi 2013-1-21 16:43
实验室仪器零售 批发  性价比高  www.yusus.net  欢迎垂询

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