The chromosomal passenger complex: one for all and all for one
阿平 添加于 2009-6-7 20:24
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作 者
Ruchaud S, Carmena M, Earnshaw WC 摘 要
The chromosomal passenger complex-composed of Aurora B kinase and its regulatory subunits INCENP, Survivin, and Borealin-modulates multiple events during mitosis. In this issue, Jeyaprakash et al. (2007) report the crystal structure of the regulatory subunit complex and reveal how interactions between these proteins promote the targeting and function of the chromosomal passenger complex during mitosis. -
详细资料
- 关键词: Cell Cycle Proteins/*chemistry/genetics/physiology; Centromere/genetics/physiology; Chromosomal Proteins, Non-Histone/*chemistry/genetics/physiology; Chromosome Segregation/genetics/*physiology; Humans; Microtubule-Associated Proteins/*chemistry/genetics/physiology; Mitotic Spindle Apparatus/genetics/*physiology; Mutation; Neoplasm Proteins/*chemistry/genetics/physiology; Protein Binding; Protein-Serine-Threonine Kinases/chemistry/genetics/physiology
- 文献种类: Journal Article
- 期刊名称: Cell
- 期刊缩写: Cell
- 期卷页: 2007年 第131卷 第2期 230-231页
- 地址: Wellcome Trust Centre for Cell Biology, Institute of Cell Biology, University of Edinburgh, Mayfield Road, Edinburgh EH9 3JR, UK
- ISBN: 0092-8674
- 备注:PMID:17956723
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